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Br J Pharmacol 182(7):14661486 Laugeray A et al (2011) Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: focus on individual differences

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Joint stiffness that is typically worse in the mornings or after periods of rest and can last for 30 minutes, 45 minutes, or even more than one hour before improving with movement

People with chronic migraines have a headache 15 or more days per month for at least three months, with eight of those days featuring symptoms like throbbing pain, nausea or light sensitivity, researchers said in background notes

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